hrp0094p1-87 | Pituitary A | ESPE2021

GHSR protects the emergence of limited sex differences in anxiety-related behaviors in adult mice after long term THC administration during peri-adolescence

Sestan-Pesa Matija , Shanabrough Marya , Horvath Tamas L. , Consolata Miletta Maria ,

As marijuana use during adolescence has been increasing, the need to understand the effects of its long-term use becomes crucial. Previous research suggested that marijuana consumption during adolescence increases the risk of developing mental illnesses, such as schizophrenia, depression, and anxiety. Ghrelin is a peptide produced primarily in the gut and is important for feeding behavior. Ghrelin and its receptor, the growth hormone secretagogue receptor (GHSR) play important...